Shimano 105 Di2 REAR DERAILLEUR 2X12s Compatibility Guide
Quick Verdict
This Shimano 105 Di2 REAR DERAILLEUR 2X12s is a Shimano Road rear derailleur. It requires a 12-speed drivetrain and compatible components. It is designed for di2 shifting systems. For best performance, use with other R7100 Series components, though it is mechanically compatible with the parts listed below.
Note on Compatibility: These recommendations are based on mechanical standards and manufacturer specifications. While parts may be technically compatible, mixing brands or categories (e.g., Road and MTB) may affect shift quality or aesthetic cohesion.
Compatible cassettes for 105 Di2 REAR DERAILLEUR 2X12s
12 total resultsRecommended Pairing
1
Shimano
105 HG CASSETTE 12s
Why it fits
- Matches required 12-speed standard
Technically Compatible
11Matches required mechanical standards, but may not be the manufacturer-intended pairing.
City / Trekking
MTB

Shimano
DEORE HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
DEORE XT HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
DEORE XT HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
SLX HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
XTR HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
XTR HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard
Road

Shimano
DURA-ACE HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
ULTEGRA HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
ULTEGRA HYPERGLIDE+ CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard
General

Shimano
HG CASSETTE 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg standard
Compatible shifters for 105 Di2 REAR DERAILLEUR 2X12s
13 total resultsRecommended Pairing
2
Shimano
105 Di2 DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
105 Di2 DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type
Technically Compatible
11Matches required mechanical standards, but may not be the manufacturer-intended pairing.
MTB / City
Road / Gravel

Shimano
DURA-ACE Di2 DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
DURA-ACE Di2 DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
DURA-ACE Di2 RIM BRAKE DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
DURA-ACE Di2 RIM BRAKE DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
GRX BRAKE LEVER (FOR FRONT SINGLE Di2)
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
ULTEGRA Di2 DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
ULTEGRA Di2 DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
ULTEGRA Di2 RIM BRAKE DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type

Shimano
ULTEGRA Di2 RIM BRAKE DUAL CONTROL LEVER 2X12s
Why it fits
- Matches required 12-speed standard
- Uses di2 shifting type
Compatible chains for 105 Di2 REAR DERAILLEUR 2X12s
10 total resultsTechnically Compatible
10Matches required mechanical standards, but may not be the manufacturer-intended pairing.
City / Trekking
General

Shimano
CHAIN DEVICE 11/12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg standard

Shimano
CHAIN DEVICE D-TYPE MOUNT
Why it fits
- Uses shimano hg standard

Shimano
CHAIN DEVICE E-TYPE MOUNT
Why it fits
- Uses shimano hg standard

Shimano
CHAIN DEVICE ISCG05 MOUNT
Why it fits
- Uses shimano hg standard

Shimano
CN-M6100 HYPERGLIDE+ CHAIN 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
CN-M7100 HYPERGLIDE+ CHAIN 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
CN-M8100 HYPERGLIDE+ CHAIN 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard

Shimano
CN-M9100 HYPERGLIDE+ CHAIN 12s
Why it fits
- Matches required 12-speed standard
- Uses shimano hg plus standard
Frequently Asked Questions
What fits with Shimano 105 Di2 REAR DERAILLEUR 2X12s?
Shimano 105 Di2 REAR DERAILLEUR 2X12s is compatible with cassettes, shifters, chains that match its technical standards. Most importantly, it requires matching 12-speed components.
Can I use a higher or lower speed chain with Shimano 105 Di2 REAR DERAILLEUR 2X12s?
No, Shimano 105 Di2 REAR DERAILLEUR 2X12s requires a 12-speed chain. Chains for different speeds have different external widths and internal profiles, which will cause poor shifting or mechanical interference.
Can I mix Shimano 105 Di2 REAR DERAILLEUR 2X12s with MTB components?
While some mechanical standards (like cassette spacing at certain speeds) may overlap, Shimano 105 Di2 REAR DERAILLEUR 2X12s is optimized for Road use. Mixing with MTB parts often fails due to differing pull ratios and chainlines.
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