Shimano GRX Di2 REAR DERAILLEUR 2x12s Compatibility Guide
Quick Verdict
Shimano GRX Di2 REAR DERAILLEUR 2x12s is a Shimano rear derailleur. It is a 12-speed component. It uses di2 shifting. Everything listed below was matched on a specification we hold for both parts: the interface each pairing actually depends on, such as freehub body, speed count, actuation or mounting standard. Where we could not verify that interface, the part is left out rather than assumed to fit.
How this list is built: a part is listed only when we hold the specification that decides the pairing for bothparts and those specifications match: the freehub body for a cassette and a wheel, the mounting interface for a chainring and a crankset, and so on. Each card shows exactly what was compared. Where we do not hold that specification the part is left out rather than assumed to fit, so this list is deliberately incomplete rather than speculative. Always confirm against the manufacturer’s own compatibility documentation before buying.
Cassettes this derailleur can wrap
13 total resultsMechanically compatible
13Every interface this pairing depends on was checked and matched, but the parts come from different ranges, so expect to confirm shift feel and finish yourself.
Road

Shimano
105 HG CASSETTE 12s
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
DURA-ACE HYPERGLIDE+ CASSETTE 12s
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
ULTEGRA HYPERGLIDE+ CASSETTE 12s (CS-R8100-12)
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
ULTEGRA HYPERGLIDE+ CASSETTE 12s (CS-R8101-12)
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts
MTB

Shimano
DEORE HYPERGLIDE+ CASSETTE 12s
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
DEORE HYPERGLIDE+ CASSETTE 12s
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
DEORE HYPERGLIDE+ CASSETTE 12s
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
DEORE XT HYPERGLIDE+ CASSETTE 12s M8100
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
DEORE XT HYPERGLIDE+ CASSETTE 12s M8200
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
SLX HYPERGLIDE+ CASSETTE 12s
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
XTR HYPERGLIDE+ CASSETTE 12s M9100
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts

Shimano
XTR HYPERGLIDE+ CASSETTE 12s M9200
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts
General

Shimano
HG CASSETTE 12s
What we checked
- Both are 12-speed
- Both are Shimano drivetrain parts
Shifters that drive this derailleur
3 total resultsRecommended
3Every interface this pairing depends on was checked and matched, and the two parts are sold as part of the same system.

Shimano
GRX Di2 DUAL CONTROL LEVER 12s RX820
What we checked
- Both are 12-speed
- Both use di2 actuation
- Both are Shimano drivetrain parts

Shimano
GRX Di2 DUAL CONTROL LEVER 2x12s
What we checked
- Both are 12-speed
- Both use di2 actuation
- Both are Shimano drivetrain parts

Shimano
GRX Di2 DUAL CONTROL LEVER 12s RX710
What we checked
- Both are 12-speed
- Both use di2 actuation
- Both are Shimano drivetrain parts
Chains for this derailleur
20 total resultsMechanically compatible
20Every interface this pairing depends on was checked and matched, but the parts come from different ranges, so expect to confirm shift feel and finish yourself.
Road / Gravel

SRAM
Apex Chain
What we checked
- Both are 12-speed

SRAM
Force Chain (CN-FRC-D1)
What we checked
- Both are 12-speed

SRAM
Force Chain (CN-FRC-E1)
What we checked
- Both are 12-speed

SRAM
RED Chain
What we checked
- Both are 12-speed

SRAM
Rival Chain (CN-RIV-D1)
What we checked
- Both are 12-speed

SRAM
Rival Chain (CN-RIV-E1)
What we checked
- Both are 12-speed
General

Shimano
CN-M6100 HYPERGLIDE+ CHAIN 12s
What we checked
- Both are 12-speed

Shimano
CN-M7100 HYPERGLIDE+ CHAIN 12s
What we checked
- Both are 12-speed

Shimano
CN-M8100 HYPERGLIDE+ CHAIN 12s
What we checked
- Both are 12-speed

Shimano
CN-M9100 HYPERGLIDE+ CHAIN 12s
What we checked
- Both are 12-speed

FSA
K-FORCE LIGHT MTB 12 SPEED CHAIN
What we checked
- Both are 12-speed
MTB

SRAM
Eagle 70 Transmission Flattop Chain
What we checked
- Both are 12-speed

SRAM
Eagle S100 Chain
What we checked
- Both are 12-speed

SRAM
Eagle S200 Chain
What we checked
- Both are 12-speed

SRAM
Eagle S500 Chain
What we checked
- Both are 12-speed

SRAM
GX Eagle Chain
What we checked
- Both are 12-speed

SRAM
GX Eagle Transmission Flattop Chain
What we checked
- Both are 12-speed

SRAM
NX Eagle Chain
What we checked
- Both are 12-speed

SRAM
X0 Eagle Transmission Flattop Chain
What we checked
- Both are 12-speed

SRAM
X01 Eagle Chain
What we checked
- Both are 12-speed
Frequently Asked Questions
What fits Shimano GRX Di2 REAR DERAILLEUR 2x12s?
On this page we list cassettes this derailleur can wrap, shifters that drive this derailleur, chains for this derailleur. Each listing was matched on a specification we hold for both parts; anything we could not verify is omitted rather than assumed to fit.
Can I use a higher or lower speed chain with Shimano GRX Di2 REAR DERAILLEUR 2x12s?
No. Shimano GRX Di2 REAR DERAILLEUR 2x12s is a 12-speed component and needs a 12-speed chain. Chains for different speed counts have different external widths and inner-plate profiles, which causes poor shifting or interference with the neighbouring sprockets.
Related compatibility guides
- Shimano ALIVIO REAR DERAILLEUR 9s Compatibility
- Shimano XTR Di2 DERAILLEUR LONG CAGE 11s Compatibility
- Shimano DEORE XT Di2 REAR DERAILLEUR MEDIUM CAGE11s Compatibility
- Shimano SLX REAR DERAILLEUR LONG CAGE 3X10s Compatibility
- Shimano TOURNEY REAR DERAILLEUR 1X6/7s Compatibility
- Shimano DEORE XT REAR DERAILLEUR 1X12s (RD-M8100-GS) Compatibility
- Shimano XTR REAR DERAILLEUR LONG CAGE 2X12s Compatibility
- Shimano SLX REAR DERAILLEUR 2X12s Compatibility
Build with this part
Start a build with this part pre-selected to verify full system compatibility and calculate total weight.
Open in BuilderThe builder re-checks the whole build every time you add a part.